CDC14A anticorps (C-Term)
Aperçu rapide pour CDC14A anticorps (C-Term) (ABIN2789804)
Antigène
Voir toutes CDC14A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- DDDVEMKNGI TQGDKLRALK SQRQPRTSPS CAFRSDDTKG HPRAVSQPFR
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Homologie
- Cow: 100%, Dog: 87%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against CDC14A. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 594 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CDC14A (CDC14 Cell Division Cycle 14 Homolog A (CDC14A))
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Autre désignation
- CDC14A
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Sujet
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The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms.
Alias Symbols: cdc14, hCDC14
Protein Interaction Partner: CHRM1, CDC6, CDC25B, POLR2A, NPM1, FZR1, TP53, CCNB1, KIF20A, BRAP,
Protein Size: 594 -
Poids moléculaire
- 66 kDa
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ID gène
- 8556
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NCBI Accession
- NM_003672, NP_003663
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UniProt
- Q9UNH5
Antigène
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